November 17, 2025
Welcome to Rejuvn8 Aesthetics, a med spa in Rochester, NY. Understanding the process of facial transformation requires understanding the distinct biological mechanisms that drive aging. Volume loss, repeated muscle contractions, fat accumulation, and diminishing collagen stores each require a specialized approach. At Rejuvn8, we provide out clients with several options for injectable treatments. Neurotoxins: Relaxing the Movement Neurotoxins: The Precise Science of Dynamic Wrinkle Prevention Target: Dynamic Wrinkles (lines that appear with facial expression) Dynamic wrinkles—such as frown lines, crow's feet, and horizontal forehead lines—are caused by the repetitive, persistent contraction of underlying facial muscles. Neurotoxins (including products like Botox, Dysport, and Xeomin) are biological agents that act at the microscopic level to interrupt this process. Mechanism of Action: The Acetylcholine Interruption The neurotoxin is injected into the targeted muscle group. The active component binds to receptors at the neuromuscular junction, the interface where the nerve sends signals to the muscle. It temporarily blocks the release of Acetylcholine—the essential neurotransmitter responsible for initiating muscle contraction. By inhibiting this signal, the muscle fibers relax, leading to the gradual and progressive smoothing of the overlying skin and the softening of Dynamic Wrinkles.  Key Applications Beyond Aesthetics: Beyond cosmetic use on the upper face, Neurotoxins are highly effective for therapeutic relief. This includes using Botox for TMJ Treatment, where targeted injections into the large masseter muscles relieve the strain and pain associated with chronic jaw clenching and grinding, which is a significant concern for many patients in the Rochester area.